Iron, a new aid in the treatment of Parkinson patients
Identifieur interne : 002967 ( Main/Exploration ); précédent : 002966; suivant : 002968Iron, a new aid in the treatment of Parkinson patients
Auteurs : W. Birkmayer [Autriche] ; D. Birkmayer [Autriche]Source :
- Journal of Neural Transmission [ 0300-9564 ] ; 1986-09-01.
Abstract
Summary: One of the problems in treating Parkinson patients is the so called “off-effect” which occurs after long term treatment with L-DOPA. Off-effects are characterized by severe rigor and akinesia. Increasing dosages of L-DOPA and decarboxylase- or monoaminooxidase-inhibitors do not improve these symptoms. Intravenously applied iron-in form of a ferri-ferro-complex-exhibited a considerable benefit for all patients treated so far. They regained a remarkable mobility. Their disability score dropped from up to 90% down to 30%. The effect of iron is dosage-dependent and lasts 24 to 48 hours.
Url:
DOI: 10.1007/BF01243354
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